Publications
JOURNAL ARTICLES:
Teratology and Percutaneous Toxicity Studies on Hair Dyes, Burnett, C., Goldenthal, E. I., Harris, S. B., Wazeter, F. X., Strausburg, J., Kapp, R. W., and Voelker, R. J. Tox. Environ. Health 1, 1027-1040, 1976.
Toxicity of Low Concentration Long-Term Exposure to an Airborne Mixture of Nitrous Oxide and Halothane, Coate, W. B., Kapp, R. W., Jr., Ulland, B. M. and Lewis, T. R. J. Environ. Toxicol. Pathol., 2:209-231, 1979.
Chronic Low-level Halothane-Nitrous Oxide Exposure: Reproductive and Cytogenetic Effects in Rats, Coate, W. B., Kapp, R. W., Jr., and Lewis, T. R. Anesthesiology 50 (4), 310-318, 1979.
An Evaluation of the Risks to Mammals of the Use of an Entomopathogenic Fungus, Nomuraea rileyi, a Biological Insecticide, Ignoffo, C. M., Garcia, C., Kapp, R. W., Jr., and Coate, W. B., Environmental Entomology, 6:354-359, 1979.
Y Chromosomal Nondisjunction in Dibromochloropropane - Exposed Workmen, Kapp, R. W., Jr., Picciano, D. J., and Jacobsen, C. B., Mutation Research, 64, 47-51, 1979.
Mutagenicity of Dimethylsulfoxide (DMSO): In Vivo Cytogenetics Study in the Rat, Kapp, R. W., Jr. and Eventoff, B. E., Teratogenesis Carcinogenesis, and Mutagenesis, 1:141-145, 1980.
Analysis of Human Spermatozoa for Y Chromosomal Nondisjunction, Kapp, R. W., Jr. and Jacobsen, C. B., Teratogenesis, Carcinogenesis, and Mutagenesis, Volume 1, 193-211, 1980.
The Embryotoxic/Teratogenic Potential of Benzene Vapor in Rats, Kuna, R. A., Kapp, R. W., Jr. Toxicol. Appl. Pharmacol. 57 (1), 1-7, 1981.
Preclinical Toxicology Studies with Acyclovir: Teratologic, Reproductive and Neonatal Tests, Moore, H. L., Jr., Szczech, G. M., Rodwell, D. E., Kapp, R. W., Jr., de Mirande, P. and Tucker, W. E., Jr. Fundam. Appl. Toxicol. 3:560-568, 1983.
The Acute Toxicity of Coal Liquefaction - Derived Materials Following Repeated Dermal Exposure in the Rabbit. McKee, R. H., Biles, R. W., Kapp, R. W., Jr., and Hinz, J. P. Journal of Applied Toxicology, 9:198-205, 1984.
Evaluation of the Systemic Toxicity of Coal Liquefaction-Derived Materials Following Repeated Dermal Exposure in the Rabbit. McKee, R. H., Kapp, R. W., Jr., and Ward, D. P. Journal of Applied Toxicology, 5:345-351, 1985.
An Evaluation of the Acute Toxic Properties of Liquids Derived from Oil Sands. Stubblefield, W. A., R. H., Kapp, R. W., and Hinz, J. P. Journal of Applied Toxicology, Volume 9 (1), 59-65 (1989).
In Vitro and In Vivo Assays of Isopropanol for Mutagenicity, Kapp, R.W. Jr., Marino, D.J., Gardiner, T.H., Masten, L.W., McKee, R.H., Tyler, T.R., Ivett, J.L., and Young, R.R. Environmental and Molecular Mutagenesis. 22:93-100 (1993).
Two Generation Reproduction Toxicity Study with Isopropanol in Rats, Bevan, C., Tyler, T.R., Gardiner, T.H., Kapp, Jr., R.W., Andrews, L. and Beyer, B.K. Journal of Applied Toxicology, 15(2), 117-123 (1995).
Isopropanol: Summary of TSCA Test Rule Studies and Relevance to Hazard Identification, Kapp, R.W, Bevan, C., Gardiner, T.H.,.R., Banton, M. I., Tyler, T.R. and Wright, G.A. Regulatory Toxicology and Pharmacology, 23:183-192 (1996).
Isopropanol Vapor Inhalation Oncogenicity Study in Fischer 344 Rats and CD-1 Mice, Burleigh-Flayer, H., Garman, R., Neptun, D., Bevan, C., Gardiner, T., Kapp, R., Tyler, T. and Wright, G. Fundamental and Applied Toxicology 36, 95-111 (1997).
Estrogen Modulation: Tiered Testing for Human Hazard Evaluation, Carney, E.W., Hoberman, A.M., Farmer, D.R., Kapp, R.W., Jr., Nikiforov, A.I., Bernstein, M., Hurtt, M.E., Breslin, W.J., Cagen, S.Z. and Daston, G.P., Reproductive Toxicology, 11(6), 879-892 (1997).
Motor Activity Effects in Female Fischer 344 Rats Exposed to Isopropanol for 90 Days, Burleigh-Flayer, H., Gill, M., Hurley, J., Bevan, C., Gardiner, T., Kapp, R., Tyler, T. and Wright, G., Journal of Applied Toxicology 18, 373-381 (1998).
Dermal Absorption and Pharmacokinetics of Isopropanol in the Male and Female F-344 Rat, Boatman, R.J., Perry, L.G., Fiorica, L. A. English, J.C., Kapp, Jr., R.W., Bevan, C., Tyler, T.R., Banton, M.I. and Wright, G.A. Drug Metabolism and Disposition 26(3), 197-202, March (1998).
Encyclopedia of Toxicology, 2nd Edition, Edited by P. Wexler. Academic Press, 2005. Author of the following topics:
1. Arsenic
2. Chromium Hexavalent Compounds
3. Clean Water Act
4. Clean Air Act
5. Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA)
6. Fluorine
7. Food Drug and Cosmetic Act
8. Isocyanates
9. Molybdenum
10. Safe Drinking Water Act
11. Tetrachloroethane
12. 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)
13. Titanium Tetrachloride
14. Tobacco Smoke
15. Toxic Substances Control Act
16. Trichloroethane
17. Vinyl Chloride
The GI Tract as the Major Route of Pharmaceutical Administration, Robert Kapp, Chapter 5 in Target Organ Toxicity: The GI Tract, 2nd Edition, S.C. Gad Editor. In press for publication in 2007.
Methods in Gastrointestinal Toxicology, Robert Kapp, Chapter 26 in Principles and Methods of Toxicology, 5th Edition, A.W. Hayes Editor. In press for publication in 2007.
Hormone Assays and Endocrine Function, Robert W. Kapp and John A. Thomas, Chapter 30 in Principles and Methods of Toxicology, 5th Edition, A.W. Hayes Editor. In press for publication in 2007.
Kapp, R.W. (Ed.) Reproductive Toxicology, Third Edition, Target Organ Toxicology Series, John A. Thomas, A. Wallace Hayes & Donald E. Gardner, Series editors, CRC Press. In preparation for publication in 2008.
Book Review: Susan Shankie. Hypertension in Focus. R.W. Kapp, Jr., International Journal of Toxicology, Volume 22, Issue 4. (2003).
Book Review: Ivan H. Stockley. Stockley’s Drug Interactions – Sixth Edition. R.W. Kapp, Jr., International Journal of Toxicology, Volume 23, Issue 1 (2004).
Book Review: Clarke’s Analysis of Drugs and Poisons – Third Edition. Anthony C. Moffatt, M. David Osselton and Brian Widdop. R.W. Kapp Jr., International Journal of Toxicology, Volume 25:81-82, 2006.
Book Review: Developmental and Reproductive Toxicology – A Practical Approach – Second Edition. Ronald D. Hood. R.W. Kapp Jr., International Journal of Toxicology, In press, January, 2007).
MAJOR REVIEWS AND BOOK CHAPTERS:
Cytogenetics Manual for the IAP Cytogenetics Workshop, Kapp, R. W., Jr. and Harris, B. L. International Academy of Pathology 1971 and 1972.
Technical Manual for Clinical Cytogenetics - Peripheral Lymphocyte and Bone Marrow Preparation Techniques, Kapp, R. W., Jr. U.S. Navy Clinical Laboratory Training Series, Bethesda Naval Hospital, 1972 - 1979.
Monitoring Y Chromosomal Nondisjunction in Humans with the YFF Sperm Test, Kapp, R. W., Jr., Benge, M. C., Picciano, D. J., Kilian, D. J., Legator, M. S., and Jacobson, C. B. Proceedings: Workshop on Methodology for Assessing Reproduction Hazards in the Workplace. DHHS (NIOSH) Publication No. 81 - 100, Pg. 307 - 326, October, 1980.
An evaluation of the mouse sperm morphology test and other sperm tests in nonhuman mammals - A report of the U.S. Environmental Protection Agency Gene-Tox Program, Wyrobek, A. J., Gordon, L., Burkhart, J. G., Francis, M. W., Kapp, R. W., Jr., Letz, G., Malling, H. V., Topham, J. C., and Whorton, M. D. Mut. Research. Vol. 115, No. 1 pp. 1-72, May, 1983.
An evaluation of human sperm as indicators of chemically induced alterations of spermatogenic function - A report of the U.S. Environmental Protection Agency Gene-Tox Program, Wyrobek, A. J., Gordon, L., Burkhart, J. G., Francis, M. W., Kapp, R. W., Jr., Letz, G., Malling, H. V., Topham, J. C., and Whorton, M. D. Mut. Research Vol. 115, No. 1 pp. 73-148, May, 1983.
Detection of Chemically Induced Y-Chromosomal Nondisjunction in Human Spermatozoa, Legator, M. S. and Kapp, R. W., Jr. In Single-Cell Mutation Monitoring Systems - Methods and Applications, Aftab A. Ansari and Frederick J. de Serres, Eds. Plenum Publishing Corporation, New York, 1984.
Current Status of Bioassays in Genetic Toxicology - The Dominant Lethal Assay: A Report of the U.S. Environmental Protection Agency Gene-Tox Program, Green, S., Auletta, A., Fabricant, J., Kapp, R., Manandhar, M., Sheu, C., Springer, J. and Whitfield, B. Mutation Research, 154: 49-67, 1985.
Toxicological Information Sources and Their Use, Robert W. Kapp, Jr. and Susan Henry. Chapter 2 in Product Safety Evaluation Handbook, 2nd Edition S. Gad, Ed., CRC Press, 1999.
OTHER PUBLICATIONS AND ABSTRACTS:
A Comparative Study of Dermal Reactions Using the Intact Rabbit Skin, Sultan, J. C., and Kapp, R. W., Jr. Abstract in Toxicol. Appl. Pharmacol. 33 (1), 87, July 1975.
A Rabbit Restraining Device, Kapp, R. W., Jr. and Strausburg, J. C. Paper presented at the AALAS Meeting, Boston, Massachusetts, November 16-21, 1975.
A Detection of the Mutagenic Potential of Selected Anticancer Agents in Man, Kapp, Robert W., Jr., and Jacobson, Cecil B. Abstract in Toxicol. Appl. Pharmacol. 37 (1), 110, July 1976.
Detection of Aneuploidy in Human Sperm, Kapp, R. W., Jr., Environmental Health Perspectives, 31:27-31, 1979.
In Vivo Cytogenetic Effects of DMSO in Rats, Kapp, R. W., Jr., and Eventoff, B. E. Paper presented at the Tenth Annual Meeting of the Environmental Mutagen Society, New Orleans, Louisiana, March 8-12, 1979.
Mutagenicity of 1, 2-Dibromo-3-Chloropropane (DBCP): In Vivo Cytogenetics Study in the Rat, Kapp, R. W., Jr., Paper presented at the Eighteenth Annual Meeting of the Society of Toxicology, New Orleans, Louisiana, March 11-15, 1979.
Inhalation Toxicity of Monochloromonofluoromethane, Coate, W. B., Voelker, R., and Kapp, R. W., Jr. Paper presented at the Eighteenth Annual Meeting of the Society of Toxicology, New Orleans, Louisiana, March 11-15, 1979.
Chemically Induced Alterations of Testicular Function in Man as Measured by Semen Analysis Parameters, Wyrobek, A. J., Burkhart, J. G., Francis, M. C., Gordon. L. A., Kapp, R. W., Letz, G., Malling, H. V., Topham, J. C., and Whorton, M. D. Paper presented at Conference on Current Status of Bioassays in Genetic Toxicology, December 3-5, 1980, National Academy of Sciences, Washington, D.C.
A Review of the Mouse Sperm Morphology Assay and Other Animal Sperm Assays, Wyrobek, A. J., Burkhart, J. G., Francis, M. C., Gordon, L. A., Kapp, R. W., Letz, G., Malling, H. V., Topham, J. C., and Whorton, M. D. Paper presented at Conference on Current Status of Bioassays in Genetic Toxicology, December 3-5, 1980, National Academy of Sciences, Washington, D.C.
Dominant Lethal Assay, Green, S., Auletta, A., Fabricant, J., Kapp, R. W., Jr., Manandhar, M., Sheu, C., and Whitfield, B. L. Paper presented at Conference on Current Status of Bioassays in Genetic Toxicology, December 3-5, 1980, National Academy of Sciences, Washington, D.C.
Body Weight Loss Induced by Food Restriction Causes Testicular Atrophy on Aspermatogenesis in Rabbits, Keller, C. A. and Kapp, R. W. Abstract in the Toxicologist 2:41 (1983).
Systemic Toxicity in the Rabbit Following Repeated Dermal Exposure to EDS Coal-Derived Liquids, D. P. Ward and R. W. Kapp, Jr., and R. H. McKee, Abstract in The Toxicologist 4:183 (1984).
A Thirteen Week Feeding Study on Diisonyl Phthalate, Bird, M. G., Kapp, R. W., Keller, C. A., and Lington, A. W. Abstract in The Toxicologist 6:184 (1986).
Two-Generation Reproduction Toxicity Study in Rats with Isopropanol, . Beyer, B.K., Tyler, T.R. Gardner, T.H. Kapp, Jr. R.W., Andrews, L., and Bevan, C. Abstract in The Toxicologist 13:75 (1993).
Isopropanol Ninety-Day Vapor Inhalation Neurotoxicity Study in Female F-344 Rats, Gill, M., Burleigh-Flayer, H., Bevan, C., Gardiner, T., Kapp, R., Tyler, T. and Wright, G. Abstract in The Toxicologist 14:97 (1994).
Isopropanol Vapor Inhalation Study in CD-1 Mice, Burleigh-Flayer, H., Bevan, C., Gardiner, T., Garman, R., Kapp, R., Neptun, D., Tyler, T. and Wright, G. Abstract in The Toxicologist 14:313 (1994).
Isopropanol (IPA) Vapor Inhalation Oncogenicity Study in Fischer 344 Rats, Garman, R., Bevan, C. Burleigh-Flayer, H.,. Gardiner, T., Kapp, R., Neptun, D., Tyler, T. and Wright, G. Abstract in The Toxicologist 322:1727 (1995).
In Vitro Penetration of Isopropanol (IPA) Through Rat, Mouse and Human Skin, Morris, E.M., Sun, J.D., Frantz, S.W., Beskitt, Bevan, C, Gardiner, T., Kapp, R., Tyler, T., and Wright, G. Abstract in The Toxicologist 183:979 (1995).
Dermal Absorption and Pharmacokinetics of Isopropanol in the Male and Female F-344 Rat, Boatman, R.J., Perry, L.G., Fiorica, L.A., English, J.C., Kapp, R.W., Jr., Bevan, C., Tyler, T.R., Banton, M.I. and Wright, G.A. Abstract in The Toxicologist 41:210 (1996).
The Use of Environmental Fate and Effects Data for MSDSs and Emergency Response Planning, Kapp, Jr., R.W., Sares, D.W., Javorek, B.C., and Strother, D.E. Abstract in Society of Environmental Toxicology and Chemistry Abstract Book, PO210, November, 1996, pp. 159.
A Weight-of-Evidence Review of Acrylonitrile Reproductive and Developmental Toxicity, Kapp, Jr., R.W., Tyl, R.W., Harris, S.B., and Strother, D.E., Abstract in The Toxicologist 36:1319 (1997).
Estrogen Modulation: Tiered Testing for Hazard Evaluation, Carney, E., Hoberman, A., Farmer, D., Kapp Jr., R., Nikiforov, A., Bernstein, M., Hurtt, M., Breslin, W., Cagen, S. and Daston, G. Abstract in The Toxicologist 36:65 (1997).
Dermal Sensitization Evaluation of Maleic Anhydride and Subsequent Reaction Materials Used in the Development of a Novel Synthetic Fiber, Glaza, S.M. Kapp, Jr., R.W. and Strother, D.E. Abstract in The Toxicologist 54(1):123 (2000).
A Combined Repeated Dose Toxicity Study and Reproduction/Developmental Screening Study in Sprague Dawley Rats with Acetophenone (OECD Guideline No. 422), Kapp, Robert W., Thorsrud, Bjorn A, Moffatt, William J, Lawton, Leonard. Abstract in The Toxicologist 72(S-1):76 (2003).
